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Officials from several countries vow to quickly determine who's behind Thursday's downing of Malaysia Airlines Flight MH-17 and the deaths of all 298 aboard.

U.S. intelligence officials confirmed that the crash was caused by a surface-to-air missile near Ukraine's border with Russia, but have yet to determine where it originated. The incident already is inflaming tensions between the two countries and escalating political rhetoric elsewhere.

It was not an accident, it was blown out of the sky,'' said Vice President Joe Biden.

Malaysia Airlines said Ukrainian air traffic control lost contact with Flight MH17 about 30 miles from Russia. There were no distress calls as the Boeing 777, carrying 283 passengers and 15 crew, began to break apart as it fell from the sky in the world's deadliest aviation incident since 9/11.

Crash victims and body parts were strewn among burning debris up to 10 miles away. Among the dead: 154 Dutch nationals, 27 Australians, 11 Indonesians, six Brits, four Germans, four Belgians, four French, three Filipinos and a Canadian.

The crash site is in Ukraine's war-torn Donetsk region, where political unrest and and scattered fighting between Ukraine and pro-Russian militants has festered for months. After the downing of several Ukraine aircraft in recent days, accusations, blame and finger-pointing over Thursday's crash was fevered.

Ukrainian President Petro Poroshenko called crash an act of terrorism' and demanded an international investigation. Ukrainian officials said they had intercepted telephone calls of a separatist leader discussing the crash with Russian military intelligence officers. Separatists initially believed they had downed a military cargo plane, according to the SBU, Ukraine's main security agency.

But Russian President Putin blamed the incident on Ukraine's government, which carries responsibility for this horrible tragedy.

We will do everything everything that depends on us, in any case to ensure that an objective picture of the events becomes accessible for our public and for the Ukrainian public and the entire world, Putin said.

In brief remarks at an appearance in Wilmington, Del., President Obama called the incident a terrible tragedy and said the U.S. will offer any services it can to determine what happened.

Said Malaysian Prime Minister Najib Razak; We must and we will find out precisely what happened to this flight. No stone will be left unturned.

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Contributing: Oren Dorell in McLean, Va., Donna Leinwand Leger in Washington, D.C., Jabeen Bhatti in Germany and the Associated Press.

Follow Doug Stanglin on Twitter: @dstanglin. follow Strauss @gstrauss_

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