San Francisco 49ers
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This seems like a no-brainer, especially since the teams will meet twice this season. Both teams have young quarterbacks whose stars are still on the rise. Colin Kaepernick led the Niners to the Super Bowl and nearly pulled off an amazing comeback win. The teams split the 2012 season series, with each team winning at home, but the Seahawks win in Week 16 (42-13) was far more dominant than the Niners win in Week 7 (13-6). This has the potential to be the Sunday nightcap of opening weekend or maybe even the third game on Thanksgiving.