Talia Castellano, the 13-year-old cancer patient who became a YouTube beauty guru, honorary CoverGirl and friend of the Ellen DeGeneres Show, died Tuesday.
"It is with a heavy heart that we share with all of you that Talia has earned her wings at 11:22am," read a statement on the official Facebook page.
"Please lift her beautiful soul, her beautiful light to heaven and please send your love and prayers to her family during this most difficult time. God speed little one, may you be free from pain and suffering, may your soul feel the light and love that you brought to so many of us on this Earth during the short time you were her with us. We will miss you more than you will ever know baby girl."
Castellano had been fighting cancer for more than six years and had been in the hospital for the last six months.
"This year I met a very special girl, and today we lost her," DeGeneres Tweeted. "Sending my heart to Talia's family. I'm so sad."