Weight loss, metabolism and genetics

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by KING 5 News

KING5.com

Posted on April 11, 2014 at 9:42 AM

Updated Friday, Apr 11 at 9:42 AM

Are you struggling with your weight but doing everything right? Your metabolism may be to blame and there could be a genetic link.

Our Get Fit doctor, Emily Cooper wrote The Metabolic Storm: The science of your metablism and why it's making you fat. She's here to continue our discussion about metabolism and how some people are pre-disposed to being overweight.

Joyce: Dr. Cooper, how does that work?
 
Dr. Cooper: As we've discussed before, when someone has a perfectly functioning metabolism, it's not hard to keep their weight in a normal range. But on the flip side, if there are glitches, the metabolic feedback loop can become a virtual obstacle course.

Joyce: You've said that sometime these glitches are passed down in families, that they're genetic.

Dr. Cooper: Yes. And an exciting big new scientific research study is being done right now studying how, for some obese people, losing weight and keeping it off can be affected by genetics. My nonprofit group, The Diabesity Research Foundation, is participating to help find people who might be right for the study.

Joyce: So what happens next?

Dr. Cooper: The portion we're helping with is a genetic screening test.  If it shows that you pre-qualify due to having a specific genetic predisposition to being overweight that the scientists are interested in, you may be asked if you would like to participate in a clinical research study where you might receive an investigational drug being studied for this type of genetic profile.  

Joyce: Who qualifies for this?

Dr. Cooper: To be screened to see if you have specific genes that may cause obesity and possibly pre-qualify for the main study, these are the basic requirements: 

  • 18 to 65 years of age
  • Body Mass Index (BMI) of 30-50
  • Do not have diabetes
  • Have not had weight-loss surgery

Contact:
Phone: 206-632-4575 X 111
Email: info@diabesityresearchfoundation.org

Joyce: You told me that the first part of testing is just a swipe of your cheek to see if you have the right gene profile.

Dr. Cooper: Yes, it's simple. Participating in this study about a root cause of obesity could potentially help millions of people in the future.  We're so excited about it!

The Diabesity Research Foundation is so grateful for this opportunity to connect with scientists who are trying to find solutions for people in the future who have suffered from obesity for most of their lives.
 

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