A laugh, sneeze or cough can trigger an embarrassing problem.
Carolyn Upton first noticed the problem in her mid-forties. The exercise enthusiast had stress urinary incontinence.
"Running, jumping jacks. All those things were really terrible for me,” she said.
She was one of 64 women picked for a first of its kind study.
Urologist Kenneth Peters is testing a non-surgical procedure to help and possibly cure stress urinary incontinence. Patients undergo a leg biopsy.
"We would take a little piece of muscle,” said Peters.
Cells from that muscle were isolated. Then, grown in the lab and separated into different doses.
"Ten million, 50 million, 100 million or 200 million cells.”
The cells are injected to help regenerate muscles that control the bladder. Six months later.
"The majority of patients had at least 50-percent reduction in their incontinence. Depending on the dose, anywhere from 20-50 percent of patients become completely dry,” said Peters.
It appears the higher the dose the better the outcomes. Carolyn says her problem is about 80-percent better since the procedure.
"It really does change your life,” she said.
A larger clinical trial in the works and could happen within the next year.