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Doctors create first vaccine to prevent urinary tract infections

by JEAN ENERSEN / KING 5 News

Bio | Email | Follow: @jeanenersen

KING5.com

Posted on April 30, 2010 at 5:40 PM

Updated Friday, Apr 30 at 6:07 PM

There's a vaccine for chicken pox, measles, mumps. Now, doctors are working to create the first vaccine to prevent urinary tract infections.

Many people get them and they'll all tell you how painful it is.

"It's like a knife-twisting pain. You're unable to even do the dishes," said Sharon DeBarnardo, UTI patient.

Debanardo knows the pain that comes with infections that invade the kidney, bladder and urinary tract. 

"I constantly went every 10 days having a bladder infection and urinary tract infection," she said. 

Fifty-three percent of women and 14 percent of men will get a UTI. That adds up to 1.3 million emergency room visits and 250,000 hospitalizations each year. The only treatment is antibiotics.

"We're beginning to see increasing resistance to these antibiotics and that's of particular concern," said Dr. Harry Mobley, University of Michigan.

Dr. Mobley and his team are working on a vaccine to prevent the infections.

"A spray up the nose, a couple doses of this, would protect the bladder," said Mobley.

Mobley shows a photo of an infected urinary tract. 

"Inside of a bladder looks like an inside-out soccer ball," he said.

An infection causes layers of cells to peel off.

"Bacteria get into this normally sterile site," Mobley said. 

After five years of study in mice, researchers found three antigens that protect against bacteria. The next  step: Try out the vaccine in humans.

"It would be fabulous," said Debanardo.

More tests are needed before there's relief for people like Debanardo, but she's hopeful a simple spray could one day solve her painful problem.

Dr. Mobley says the vaccine is still three to five years away from hitting the market.

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Comments: Displaying 1 - 3 of 3

deborah51 said on May 4, 2010 at 11:53 AM

I can't wait.! I have been plagued with urinary infections since I was eight years old. They have been especially bad these past 2 years. - constant ! I am now allergic to three antibotics that I used to use for these infections. I'm running out of meds to take. This vaccine would be gift for me.

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lilredcv said on May 1, 2010 at 10:22 PM

I, too, have had a UTI or two over the course of my life. However, it's not enough to want to go shoot myself up with yet another vaccine to "prevent" them! We live in a very chemical world and we get enough of them shoved into our systems as it is with the other vaccines available and in our foods. I'm definitely passing on this one.

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red117 said on April 30, 2010 at 9:48 PM

I've had a UTI twice now in the last four years so that's not too bad, but it was still a terrible annoyance. Always felt like I had to urinate and doing so was painful and it smelled really really bad so it's also embarrassing. I'm really glad to hear they've found a way to bring UTI's down.

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