Have doctors found a cure for MRSA?


by KING 5 HealthLink


Posted on October 14, 2010 at 5:45 PM

Updated Friday, Jan 4 at 10:44 AM

MRSA Kills 19,000 people per year in the U.S. Another bacteria similar to MRSA, called MDRAB, is now attacking war vets, many of them infected by improvised explosive devices. In a recent study, 10 percent of Iraqi vets treated had the infection. Now, a creation from inside the lab may soon help soldiers and civilians win the battle against bacteria.

Soap and water and hand sanitizer don't always hold up when it comes to MRSA. It's resistant to almost all antibiotics and was enough to knock Christopher Flynn out cold.

"I went to bed one day because I felt achy, and I basically woke up 10 days later,"  he said.

The bacteria attached itself to Christopher's hip implant and spread throughout his body.

Professor Dr. Christian Melander may have the solution. It's a compound called SPAR or "Suppressor of Antibiotic Resistance," and it cracks drug-resistant codes.

"It's the first thing that I've ever seen this happen with, and I've looked," he said.

These infections build defensive walls that resist antibiotics. SPAR turns off the genes that make those walls, allowing standard drugs to work again.

"In the presence of our compound, those genes can't be turned on, and they act just like regular bacteria, " said Melander

Melander's SPAR substance is made in the lab and is a salt of an organic compound. It's been successful during in-vitro studies, and animal-based studies are on the horizon. Meanwhile, his staff is working with Walter Reed Army Medical Center to see if SPAR helps prevent additional war wounds.