SEATTLE (AP) - Josh Reddick homered, Brian McCann added a three-run double and Lance McCullers pitched into the sixth inning in his return from the disabled list to lift the Houston Astros to a 5-2 victory over the Seattle Mariners on Saturday night.

McCullers (7-1), who had been sidelined with lower back discomfort, allowed one run on four hits in five-plus innings. He struck out eight and walked none in his first start since June 8.

Reddick staked the Astros to a 2-0 lead in the third with his eighth home run. George Springer singled to open and Reddick drove a 1-0 pitch from Sam Gaviglio (3-2) over the wall in center.

McCann's seventh-inning double increased the lead to 5-1.

Seattle, which had won six straight, scored one in the ninth off Ken Giles on a double and three consecutive walks, but Carlos Ruiz struck out looking with the bases loaded.