BERKELEY, Calif. — Twenty years after the movie “Contact” brought the search for extraterrestrial intelligence, or SETI, to the big screen, it’s dawning on astronomers that the real-world plotline might turn out to be totally different 20 years from now.

So far, SETI has been dominated by radio telescope surveys looking for anomalous patterns that may point to alien transmissions. But SETI’s practitioners are realizing that E.T. may make its presence known in other ways.

Over the next 20 years, or 200 years, SETI may come to stand for sensing extraterrestrial irregularities, ranging from unusual atmospheric chemistry to higher-than-expected thermal emissions. The telltale signs of life beyond our solar system may even be associated with phenomena we haven’t yet come across.

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